10 Best Pet Stain Removers 2025 in the United States

The Rocco & Roxie Stain & Odor Eliminator is an impressive product for addressing pet-related stains and odors. Its enzymatic formula is designed to tackle tough stains like pet urine, feces, vomit, and other organic spills by breaking down the ammonia crystals and organic matter. One of its standout features is its safety; it’s chlorine-free, color-safe, and certified gentle for use around pets and children, which makes it a worry-free option for households with animals.

Nature’s Miracle Advanced Stain and Odor Eliminator Dog Spray is designed for tackling severe dog messes including urine, diarrhea, and vomit. The enzymatic formula is a standout feature, as it continues to break down and eliminate stains and odors as long as the bio-based mess is present. This makes it highly effective for persistent or tough stains. Additionally, the formula helps discourage resoiling by removing the odor completely, which is beneficial for pet owners dealing with recurring accidents.

The Simple Solution Extreme Pet Stain and Odor Remover is an enzymatic cleaner designed to tackle the toughest pet stains and odors with three times the cleaning power of regular formulas. This product is highly effective for removing dog and cat messes like urine, feces, and vomit from various surfaces including carpet, upholstery, bedding, fabrics, and other water-safe areas. Its enzymatic formula not only cleans but also helps prevent pets from marking the same spot again.